Pyoderma gangrenosum: ulcers on the skin that get bigger
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With pyoderma gangrenosum you suffer from ulcers on the skin that gradually enlarge. Pyoderma gangrenosum is a rare condition in which large, painful sores (ulcers) develop on the skin, usually on your legs, and slowly enlarge. The ulcers develop spontaneously or after damage to the skin. It is not known exactly what causes pyoderma gangrenosum, but it turns out to be a disorder of the immune system. People with certain underlying conditions, such as inflammatory bowel disease or rheumatoid arthritis, have a greater risk of developing pyoderma gangraenosum. So it is not caused by a bacterial infection. The sores that occur with pyoderma gangraenosum can develop quickly. They usually respond well to treatment, often leaving scars and recurrence is not excluded.
Pyoderma gangrenosum
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What is pyoderma gangrenosum? Who gets this condition? Is the condition contagious? Cause of pyoderma gangrenosum Symptoms: Sores on the skin that get bigger Diagnosis and research How is pyoderma gangrenosum treated? Wound care Topical corticosteroid or systemic treatment Pain relief Outlook
Cause of pyoderma gangrenosum
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The cause of pyoderma gangrenosum is unknown. However, there are strong indications that it concerns a disorder of the immune system, a runaway inflammatory reaction in which a lot of white blood cells (leukocytes)
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Diagnosis and investigation
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Clinical picture
Outlook
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Once treatment has started, recovery will begin. However, it may take months to years for full recovery to occur. This is an intense experience. In the meantime, the disease can flare up. Eventually the sores and wounds will heal completely, sometimes leaving scars. This depends on the size and depth of the sores. The course of the treatment varies. You can be affected by pyoderma gangrenosum once, but it also happens that with every (minor) skin damage you will again suffer from pyoderma gangrenosum ulcers. But because you then know what you have, you can intervene early and stop the formation of ulcers. It is also possible for the ulcers to come back spontaneously, sometimes requiring continuous systemic treatment with prednisone to prevent the ulcers from coming back. That is very stressful.