Gout: Causes and Treatment
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Gout is a painful rheumatic inflammation of the joints. This inflammation is caused by the formation of uric acid crystals in the joint. The inflammation occurs most frequently in the big toe, which is why the condition is commonly referred to as the paw.
Causes and Treatment of Gout
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What should the patient with gout take into account? How Is Gout Treated? Inhibition of uric acid production with uricostatics Stimulation of uric acid excretion with uricosurics Inhibition of leukocyte migration to the joint Administer anti-inflammatory and analgesic medications
What should the patient with gout take into account?
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A patient suffering from gout should take the following general advice into account:
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11 minMain dishpeanut oil, tofu stir-fry cubes finely seasoned, stir fry sauce sweet and sour, thick noodles, carrot julienne, beetroot julienne, yellow bell pepper, watercress,rainbow salad with tofu -
45 minMain dishRed cabbage, mild olive oil, quinoa plus, forest outing, lemon, sesame oil, soy sauce less salt, Bio Today tahini white in pot, tap water,grilled red cabbage with quinoa salad -
30 minDessertBrie, Roquefort, port salut, gruyere, Camembert, walnut, garlic, thyme, honey, grape, baguette, Red onion, red grape, raisins, Red wine, Red wine vinegar, Brown sugar,generous cheese plate with onion marmalade -
30 minDessertFull Milk, whipped cream, macaroon, custard powder, vanilla sugar, sugar, protein, amaretto, almond liqueur, basic recipe cooking pears,macaroon pastry with casserole
How is gout treated?
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The aim of treatment is to reduce the symptoms of the acute attack and prevent new attacks. The following strategies are used for this:
Inhibition of uric acid production with uricostatics
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The most commonly used uricostatics are allopurinol and febuxostat. The pharmacological effect of allopurinol is due to a metabolite of the compounds, namely alloxanthin. The latter is an inhibitor of the xanthine oxidase, an enzyme that is important for the production of uric acids. Febuxostat also works according to the same pharmacological principle.
Stimulation of uric acid excretion with uricosurics
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The most commonly used uricosuric agent is probenecid. Uric acids are freely filtered at the glomerulus in the kidneys, after which they are partially reabsorbed in the proximal tubule. Probenecid will counteract this reabsorption, increasing the excretion of the harmful uric acids.
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5 minDrink without alcoholbananas, cool fresh apple-pear raspberry juice, Soy drink vanilla,soy fruit shake -
20 minMain dishsauerkraut, sticking potato, liquid baking product, half-to-half minced, Spice meatballs, pineapple, olive oil, liquid baking product,gratin sauerkraut dish with minced meat -
40 minMain dishlemongrass, fresh ginger, Red peppers, onions, tomato cubes, fresh cod fillet, coriander, oil, ground turmeric (koenjit), coconut milk, salt,fish in creamy coconut sauce -
15 minSide dishsweet potato, soft goat cheese, egg, spring / forest onion,stuffed sweet potato with egg
Inhibition of the migration of leukocytes to the joint
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By inhibiting the migration of leukocytes, the inflammatory reaction in the joint is canceled. Colchicine is often used for this. The compound is administered early during an acute attack, resulting in an efficient anti-inflammatory response within 12 to 24 hours.
Administer anti-inflammatory and analgesic medications
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NSAIDs, or non-steroidal anti-inflammatory drugs, are the basis for adequate anti-inflammatory treatment. They are used as a first choice for acute gout attacks. Indomethacin, naproxen and diclofenac are the most commonly used NSAIDs for the treatment of gout. In addition to NSAIDs, glucocorticoids are also used in acute gout attacks.